5-Amino-1MQ — Research Overview

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a selective NNMT (Nicotinamide N-Methyltransferase) inhibitor that has emerged as a compound of significant interest in metabolic, longevity, and neurological research.

By targeting NNMT, 5-Amino-1MQ disrupts the enzymatic conversion of nicotinamide to 1-methylnicotinamide, which laboratory studies indicate leads to increased NAD+ availability, enhanced mitochondrial function, and improved metabolic efficiency in research models.

Available from 4LD in 20mg and 50mg lyophilized form, this compound is produced under quality-controlled conditions for qualified researchers and laboratory professionals working in in-vitro and controlled research settings only.

Areas of Active Research

5-Amino-1MQ has been studied across several active research areas. In metabolic research, studies suggest it suppresses NNMT activity leading to increased NAD+ levels and enhanced mitochondrial function, with animal models indicating potential effects on adipose tissue browning and thermogenesis through conversion of white adipose tissue to beige and brown adipose tissue.

In anti-aging and longevity research, preclinical models have examined its potential to reverse age-related NAD+ decline, support sirtuin activation, and reduce markers of cellular senescence in fibroblast models. In neurological research, emerging studies have explored its potential to support brain NAD+ levels, reduce amyloid-beta accumulation in Alzheimer's models, and improve cognitive function in aged animal subjects.

All findings referenced are from preclinical and in-vitro studies. This product is intended solely for laboratory research by qualified professionals and is not for human or animal consumption. 4LD makes no therapeutic claims regarding this compound.